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師資隊伍
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鄒漢勛教師個人簡介

2024年04月07日 08:44  點擊:[]

一、個人簡介

鄒漢勛,1986年出生,副教授,碩士生導(dǎo)師(資源與環(huán)境、生物與醫(yī)藥專業(yè))。博士畢業(yè)于中國科學(xué)院大學(xué)有機化學(xué)專業(yè),先后就職于新加坡眼科研究所和中國科學(xué)院福建物質(zhì)結(jié)構(gòu)研究所,20239月以高層次人才引進(jìn)至莆田學(xué)院環(huán)境與生物工程學(xué)院工作,入選福建省高層次人才(C類)。主要從事超分子化學(xué)、有機熒光探針和生物傳感與疾病診療等方面研究工作。近年來在Journal of the American Chemical Society、CCS Chemistry,Journal Of Medicinal Chemistry、Chinese Chemical LettersACS Applied Materials & InterfacesOrganic Chemistry Frontiers等國內(nèi)外高水期刊發(fā)表論文近30篇,申請國內(nèi)、國際專利9項;目前主持國家自然科學(xué)基金一項,福建省自然科學(xué)基金一項。

 

教育經(jīng)歷:

2017.09-2020.09中國科學(xué)院大學(xué)博士有機化學(xué)

2009.09-2012.06 華南理工大學(xué)碩士有機化學(xué)

2005.09-2009.06 青島大學(xué)本科化學(xué)

 

工作經(jīng)歷:

2023.09-至今莆田學(xué)院環(huán)境與生物工程學(xué)院副教授

2016.02-2023.08中國科學(xué)院福建物質(zhì)結(jié)構(gòu)研究所助理研究員

2012.07-2016.01新加坡眼科研究所助理研究員

 

聯(lián)系方式:hanxun_zou@163.com

 

二、科研項目

1.基于動態(tài)共價化學(xué)的近紅外二區(qū)發(fā)光組裝體構(gòu)筑及調(diào)控研究,國家自然科學(xué)基金青年項目,22101283,2022-012024-12,30萬元,在研,主持

2. 比率型近紅外二區(qū)熒光示蹤的腫瘤診療前藥構(gòu)建及其精準(zhǔn)響應(yīng)控釋研究,福建省自然科學(xué)基金面上項目,2024J011310122024-052027-04,10萬元,在研,主持

3. 高反應(yīng)性比率型近紅外二區(qū)熒光探針設(shè)計及其在肝癌診斷的應(yīng)用探索,莆田學(xué)院交叉學(xué)科專項-工科/醫(yī)科,ZY2400962024-072027-07,5萬元,在研,主持

三、科研成果

論文著作

(1) L. Wang, #H. Zou, # H. Ye, Y. Hai, H. Lu, J., Deng, L. You*. Photoswitchable Molecular Recognition Enabled by Dithienylethene-Mediated Structural Changes of Dynamic Covalent Hydrazone Bonds. CCS Chemistry, 2024, 6, 497-506. 中國科學(xué)院一區(qū),IF = 11.2.

(2) G. Jiang, L. Wang, H. Ye, H. Zou*, L. You*. Dynamic Covalent Reactions and Chirality Sensing with Diphenylethene Derived Hemiaminals. ChemPlusChem, 2023, e202300080. 中國科學(xué)院三區(qū), IF = 3.21

(3) S. Qin, H. Zou*, Y. Hai, L. You*. Aggregation-induced emission luminogens and tunable multicolor polymer networks modulated by dynamic covalent chemistry. Chin. Chem. Lett.2022, 33, 3267-3271. 中國科學(xué)院一區(qū),IF = 8.455

(4) Z. She, H. Zou*, L. You*. Tuning the selectivity of amino acid recognition with dynamic covalent bond constrained fluorophores in aqueous media. Org. Biomol. Chem. 2022, 20, 6897-6904. 中國科學(xué)院三區(qū),IF = 3.89

(5) F. Sattar, Z. Feng, H. Zou*, H. Ye, Y. Zhang*, L. You*. Dynamic covalent bond constrained ureas for multimode fluorescence switching, thermally induced emission, and chemical signaling cascades. Org. Chem. Front. 2021, 8, 3760-3769. 中國科學(xué)院一區(qū),IF = 5.456

(6) I. Khan, J. Wang, H. Zou*, H. Ye, D. Zha, Y. Zhang*, L. You*. Noncovalent and dynamic covalent chemistry strategies fordriving thermoresponsive phase transition with multistimuli andControlled Encapsulation/Release. ACS Appl. Mater. Interfaces,2020, 12, 2962?2973.中國科學(xué)院二區(qū),IF = 10.383

(7) H. Zou,# Y. Hai,# H. Ye, L. You*. Dynamic covalent cwitches and communicating networks for tunable multicolor luminescent systems and vapor-responsive materials. J. Am. Chem. Soc. 2019, 141, 41, 16344-16353. 中國科學(xué)院一區(qū),IF = 15.0

(8) Y. Hai,#H. Zou,#H. Ye, L. You*. Three switchable orthogonal dynamic covalent reactions andcomplex networks based on the control of dual reactivity. J. Org. Chem.2018, 83, 9858?9869.中國科學(xué)院二區(qū),IF = 4.198

(9) J. -J. Koh,#H. Zou,# S. Lin, H. Lin, R. T. Soh, F. H. Lim, W. Luan Koh, J. Li, R. Lakshminarayanan, C. Verma, D. T. H. Tan, D. Cao*, R. Beuerman*, S. Liu*; Nonpeptidic amphiphilic xanthone derivatives: structure-activity relationship and membrane-targeting properties , J. Med. Chem., 2016, 59, 171-193. 中國科學(xué)院一區(qū),IF = 8.039

(10) H. Zou,# J.-J. Koh,# J. Li, S. Qiu, T. T. Aung, H. Lin, R. Lakshminarayanan, X. Dai, C. Tang, F. H. Lim, L. Zhou, A. L. Tan, C. Verma, D. T. H. Tan, H. S. O. Chan, P. Saraswathi, D. Cao*, S. Liu*, R. Beuerman*; Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity, J. Med. Chem., 2013, 56, 2359-2373.中國科學(xué)院一區(qū),IF = 8.039

(11) C. Yin,#H. Ye,# Y. Hai, H. Zou,L. You*. Aromatic-Carbonyl Interactions as an Emerging Type of Non-Covalent Interactions. Adv. Sci.2024, doi.org/10.1002/advs.202310337.中國科學(xué)院一區(qū),IF = 15.1

(12) H. Lu, H. Ye, M. Zhang, Z. Liu, H. Zou, L. You*. Photoswitchable dynamic conjugate addition-elimination reactions as a tool for light-mediated click and clip chemistry. Nat. Commun.2023,14, 4015.中國科學(xué)院一區(qū),IF = 16.6

(13) C. Yin, H. Lu, H. Ye, Z. Feng, H. Zou, M. Zhang and L. You*. Double n→π* Interactions with One Electron Donor: Structural and Mechanistic Insights. Org. Lett.2023, 25, 1470?1475. 中國科學(xué)院一區(qū),IF = 5.2

(14)Q. Hu, Y. Liu, W. Li, Y. Wang, W. Liao, H. Zou, J. Li*, X. Huang*. Enhanced photocatalytic hydrogen evolution under visible-light using C, N Co-doped mesoporous TiO2 nanocrystals templated by ionic liquids.Chem. Eng. J. 2023, 451, 138670. 中國科學(xué)院一區(qū),IF = 15.1

(15)Y. Hai, H. Ye, Z. Li, H. Zou, H. Lu, and L. You*. Light-induced formation/scission of C-N, C-O, and C-S bonds enables switchable stability/degradability in covalent systems.J. Am. Chem. Soc. 2021, 143, 20368–20376.中國科學(xué)院一區(qū),IF = 15.0

 

知識產(chǎn)權(quán)

(1)Hanxun Zou, Rajamani Lakshminarayanan, Lei Zhou,Chang chuiCharles Tang, Jun-Jie Koh, Donald Tan, Chandra Verma, Roger W. Beuerman,Shouping Liu,Padmanabhan Saraswath. Derivatives of Xanthone Compounds. Pub. No.:WO/2013/036207; International Application No.: PCT/SG2012/000328.(已授權(quán))

(2) 尤磊、鄒漢勛、葉何波.一種熒光開關(guān)及其制備方法、應(yīng)用。專利號:201910092023.2 (已授權(quán))

(3)尤磊、海宇、葉何波、鄒漢勛、陸涵葳、李紫毅. 二噻吩乙烯內(nèi)酯類化合物以及制備、光調(diào)控方法。專利號:202110184683.0(已授權(quán))

(4) 尤磊、姜國山、海宇、鄒漢勛、環(huán)鏈異構(gòu)二苯乙烯熒光分子以及制備方法、應(yīng)用。專利號:202110184903.X(已授權(quán))

(5) 尤磊、海宇、葉何波、鄒漢勛、陸涵葳、李紫毅. 一種芳基乙烯內(nèi)酯類化合物及其制備方法、應(yīng)用。專利號:202110471450.9

(6) 尤磊、鄒漢勛、馮澤林、陸涵葳. 一種脲化合物其制備方法、應(yīng)用。專利號:202110443727.7

(7)尤磊、鄒漢勛、張翼. 一種基于1,8-萘二甲酰亞胺的水溶性熒光探針及其制備方法和應(yīng)用。專利號:201910246470.9

(8)尤磊、陸涵葳、葉何波、章梅蘭、鄒漢勛.一種2-(乙氧基亞甲基)1,3-二酮二噻吩乙烯衍生物及其制備方法和應(yīng)用。專利號:202210948443.8

(9)尤磊、陸涵葳、葉何波、章梅蘭、鄒漢勛。一種二噻吩乙烯1,3-二酮化合物及其制備方法、應(yīng)用。專利號:202210947333.X

 

個人榮譽

2022年獲“福建省高層次人才(C類)”榮譽稱號

 

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